Across TCGA patient cohorts, STMN3 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STMN3-associated genes across cancer lineages are EGFR_pY1068, GAPDH, and PI3K-p85. Each is linked with STMN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both STMN3-to-partner and partner-to-STMN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STMN3→partner) and Y-score (partner→STMN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.276	-3.321	.036	.010	3	1
UCEC	GAPDH →	+0.839	+3.321	.002	.010	3	1
UCEC	PI3K-p85 →	+0.247	+2.817	.024	.036	3	1
UCEC	TIGAR →	+0.208	+3.348	.009	.005	3	1
UCEC	NF2 →	+0.235	+3.321	.038	.010	2	1
UCEC	mTOR_pS2448 →	-0.231	-3.321	.003	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

STMN3 survival (RNA) · tumor vs normal (RNA) · all STMN3 data types