STMN2

Across TCGA patient cohorts, STMN2 mutation is significantly associated with the RNA expression of many other genes, with 176 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible STMN2-associated genes across cancer lineages are RN7SKP117, IL9RP4, and SSX4. Each is linked with STMN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STMN2-to-partner and partner-to-STMN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP117 grouped by STMN2-low versus STMN2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STMN2→partner) and Y-score (partner→STMN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SKP117 →	+0.157	+5.197	<.001	.003	3	2
LUAD	IL9RP4 →	+0.104	+4.426	.006	.006	3	2
LUAD	SSX4 →	+0.034	+5.315	.002	.003	3	2
BLCA	OR51A3P →	+0.064	+4.444	<.001	.006	3	2
BLCA	PTPRT-AS1 →	+0.025	+4.147	<.001	.009	3	2
BLCA	LINC01817 →	+0.035	+4.814	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 176 associations by consensus.

RN7SKP117 by STMN2 expression — LUAD

Explore this box plot interactively →