STMN2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STMN2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible STMN2-associated genes across cancer lineages are Eosinophils, Neutrophils, and CD8+ Tem. Each is linked with STMN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STMN2-to-partner and partner-to-STMN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by STMN2-low versus STMN2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STMN2→partner) and Y-score (partner→STMN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCEosinophils →+0.038+3.173.008.04931
LUSCNeutrophils →+0.016+3.469<.001.03131
UCECCD8+ Tem →+0.004+4.896<.001.03631
UCECMast cells →+0.018+3.212.041.01011
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Eosinophils by STMN2 expression — LUSC

Box plot of Eosinophils in STMN2-low vs STMN2-high samples in LUSC.

Explore this box plot interactively →

Exploration