STMN1

Across TCGA pan-cancer cohorts, STMN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated STMN1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher STMN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated STMN1 expression acts as an unfavorable survival marker.

HNSC, PDAC, and CCRCC are the cancer types where STMN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.163	0.802	.017	17	view →
PDAC	OS	Tertile	III,IV	0.293	0.832	.007	16	view →
CCRCC	OS	Tertile	All	0.681	1.000	.013	9	view →
LUAD	OS	Quartile	II,III,IV	0.373	0.788	.025	5	view →
LSCC	DFS	Median	III,IV	0.882	1.000	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

STMN1–HNSC (DFS)

Open the HNSC breakdown →