STMN1

Across TCGA cell cohorts, STMN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,047 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STMN1-associated GO terms across cancer lineages are Microtubule cytoskeleton organization involved in mitosis, Mitotic spindle organization, and Attachment of spindle microtubules to kinetochore. Each is linked with STMN1 in more than 19 cancer types. Because this analysis shows association rather than direction, both STMN1-to-partner and partner-to-STMN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule cytoskeleton organization involved in mitosis grouped by STMN1-low versus STMN1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STMN1→partner) and Y-score (partner→STMN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Microtubule cytoskeleton organization involved in mitosis →	+0.105	+1.653	<.001	<.001	3	20
OESOPHAGUS	Mitotic spindle organization →	+0.107	+1.282	.002	.003	3	19
URINARY_TRACT	Attachment of spindle microtubules to kinetochore →	+0.150	+1.826	<.001	.002	3	19
CNS	Nuclear division →	+0.083	+0.927	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic sister chromatid separation →	+0.166	+1.223	.004	.006	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of sister chromatid segregation →	+0.166	+1.223	.004	.006	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,047 associations by consensus.

Microtubule cytoskeleton organization involved in mitosis by STMN1 expression — BLOOD_Myeloma

Explore this box plot interactively →