Across TCGA patient cohorts, STKLD1 mutation is significantly associated with the RNA expression of many other genes, with 2,004 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STKLD1-associated genes across cancer lineages are MIR5589, RNA5SP325, and TBC1D26-AS1. Each is linked with STKLD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both STKLD1-to-partner and partner-to-STKLD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STKLD1→partner) and Y-score (partner→STKLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR5589 →	+0.174	+4.025	<.001	.007	3	3
CESC	RNA5SP325 →	+0.169	+4.837	<.001	.003	3	2
CESC	TBC1D26-AS1 →	+0.459	+4.236	<.001	.001	3	2
LUSC	MIR5002 →	+1.161	+5.093	<.001	.008	3	2
COAD	GAPDHP17 →	+0.080	+4.721	<.001	.004	3	2
BRCA	CICP18 →	+0.019	+5.250	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,004 associations by consensus.

Exploration

STKLD1 survival (RNA) · tumor vs normal (RNA) · all STKLD1 data types