STKLD1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STKLD1 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STKLD1-associated genes across cancer lineages are ASNS, C-Raf, and Cyclin-B1. Each is linked with STKLD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STKLD1-to-partner and partner-to-STKLD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STKLD1→partner) and Y-score (partner→STKLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECASNS →+0.515+2.321<.001.03332
UCECC-Raf →+0.188+2.222<.001.01032
UCECCyclin-B1 →+0.489+1.678.023.02332
UCECeIF4E →+0.168+3.183.037.00931
UCECKu80 →+0.195+1.335.031.04631
UCECMEK1 →+0.306+2.321.029.03331
Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration