Across TCGA pan-cancer cohorts, STK40 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated STK40 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher STK40 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated STK40 expression acts as an unfavorable survival marker.

GBM and LSCC are the cancer types where STK40 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.288	0.714	.024	9	view →
LSCC	OS	Median	II,III,IV	0.222	0.870	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: STK40 tumor-vs-normal RNA expression · all STK40 data types