Across TCGA patient cohorts, STK40 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible STK40-associated GO terms across cancer lineages are RNA secondary structure unwinding, Regulation of autophagosome maturation, and Regulation of small GTPase mediated signal transduction. Each is linked with STK40 in more than 25 cancer types. Because this analysis shows association rather than direction, both STK40-to-partner and partner-to-STK40 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STK40→partner) and Y-score (partner→STK40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	RNA secondary structure unwinding →	+0.136	+0.640	<.001	<.001	3	26
SCLC	Regulation of autophagosome maturation →	+0.121	+0.627	<.001	<.001	3	26
SCLC	Regulation of small GTPase mediated signal transduction →	+0.035	+0.545	<.001	<.001	3	26
SCLC	RISC complex assembly →	+0.098	+0.616	<.001	<.001	3	26
SCLC	Negative regulation of macroautophagy →	+0.090	+0.659	<.001	<.001	3	25
SCLC	Regulation of cell projection assembly →	+0.034	+0.530	<.001	.001	2	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

Exploration

STK40 survival (RNA) · tumor vs normal (RNA) · all STK40 data types