Across TCGA patient cohorts, STK40 protein abundance is significantly associated with the RNA expression of many other genes, with 615 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STK40-associated genes across cancer lineages are SPAG1, TJP3, and EHD1. Each is linked with STK40 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK40-to-partner and partner-to-STK40 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK40→partner) and Y-score (partner→STK40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPAG1 →	+1.462	+0.465	.008	.008	3	1
LSCC	TJP3 →	+2.049	+0.693	.008	.009	3	1
LSCC	EHD1 →	+1.339	+0.465	.001	.008	3	1
LSCC	SLC35F2 →	+1.764	+0.465	.001	.008	3	1
LSCC	NR5A2 →	+0.615	+0.465	.002	.008	3	1
LSCC	BCL2L14 →	+1.236	+0.465	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 615 associations by consensus.

Exploration

STK40 survival (RNA) · tumor vs normal (RNA) · all STK40 data types