Across TCGA patient cohorts, STK40 mutation is significantly associated with the RNA expression of many other genes, with 1,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK40-associated genes across cancer lineages are DHRS11, ALKBH1, and GABRE. Each is linked with STK40 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK40-to-partner and partner-to-STK40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK40→partner) and Y-score (partner→STK40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DHRS11 →	+0.411	+1.939	.003	.008	3	2
UCEC	ALKBH1 →	+0.317	+2.244	.005	<.001	3	2
UCEC	GABRE →	-0.675	-2.201	.001	<.001	3	2
UCEC	GSR →	+0.619	+2.721	.001	.003	3	2
UCEC	PFN1 →	+0.321	+3.042	.005	<.001	3	2
UCEC	MED31 →	+0.408	+4.191	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,329 associations by consensus.

Exploration

STK40 survival (RNA) · tumor vs normal (RNA) · all STK40 data types