Across TCGA patient cohorts, STK40 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK40-associated genes across cancer lineages are PCNA, TFRC, and ERK2. Each is linked with STK40 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK40-to-partner and partner-to-STK40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK40→partner) and Y-score (partner→STK40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.219	+1.502	.005	.030	3	2
UCEC	TFRC →	+0.474	+2.247	.015	.001	3	2
UCEC	ERK2 →	+0.238	+1.847	<.001	.008	3	1
UCEC	GAPDH →	+0.397	+3.321	.044	.009	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.374	+1.594	.045	.042	3	1
UCEC	MEK1 →	+0.522	+3.906	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

STK40 survival (RNA) · tumor vs normal (RNA) · all STK40 data types