STK4

Across TCGA cell cohorts, STK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,011 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible STK4-associated GO terms across cancer lineages are RNA localization, Regulation of centriole-centriole cohesion, and Promoter clearance during DNA-templated transcription. Each is linked with STK4 in more than 14 cancer types. Because this analysis shows association rather than direction, both STK4-to-partner and partner-to-STK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by STK4-low versus STK4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STK4→partner) and Y-score (partner→STK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RNA localization →	+0.082	+0.996	<.001	<.001	3	15
BREAST	Regulation of centriole-centriole cohesion →	+0.141	+0.710	<.001	<.001	3	14
SOFT_TISSUE	Promoter clearance during DNA-templated transcription →	+0.119	+0.723	<.001	.006	3	14
SOFT_TISSUE	RNA polymerase II promoter clearance →	+0.119	+0.723	<.001	.006	3	14
BLOOD_Lymphoma	Positive regulation of hippo signaling →	+0.112	+0.766	<.001	<.001	3	14
SOFT_TISSUE	Protein localization to chromosome →	+0.078	+0.564	<.001	.006	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,011 associations by consensus.

RNA localization by STK4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →