Across TCGA patient cohorts, STK39 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK39-associated genes across cancer lineages are Shc_pY317, EGFR_pY1068, and mTOR_pS2448. Each is linked with STK39 in more than 2 cancer types. Because this analysis shows association rather than direction, both STK39-to-partner and partner-to-STK39 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK39→partner) and Y-score (partner→STK39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.180	-2.087	<.001	.005	3	3
UCEC	EGFR_pY1068 →	-0.269	-2.584	<.001	.001	3	2
UCEC	mTOR_pS2448 →	-0.108	-2.687	.021	.005	3	2
UCEC	ATM →	-0.430	-2.209	.002	.009	3	2
UCEC	4E-BP1 →	+0.352	+3.906	<.001	<.001	3	2
UCEC	EGFR →	-0.153	-2.089	.002	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

STK39 survival (RNA) · tumor vs normal (RNA) · all STK39 data types