STK36

Across TCGA cell cohorts, STK36 mutation is significantly associated with the RNA expression of many other genes, with 146 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STK36-associated genes across cancer lineages are MYL10, OR5V1, and SERPINA7. Each is linked with STK36 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK36-to-partner and partner-to-STK36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYL10 grouped by STK36-low versus STK36-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK36→partner) and Y-score (partner→STK36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYL10 →	+0.018	+4.569	<.001	.003	3	2
LUNG_NSCLC_LUAD	OR5V1 →	+0.023	+4.947	.001	.001	3	2
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1orf158 →	+0.053	+4.807	<.001	.006	3	1
BLOOD_Myeloma	NRAP →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CBLN4 →	+0.026	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 146 associations by consensus.

MYL10 by STK36 expression — BLOOD_Leukemia

Explore this box plot interactively →