STK35

Across TCGA patient cohorts, STK35 protein abundance is significantly associated with the RNA expression of many other genes, with 7,034 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible STK35-associated genes across cancer lineages are PCAT6, MRPS26, and DNAJA4. Each is linked with STK35 in more than 2 cancer types. Because this analysis shows association rather than direction, both STK35-to-partner and partner-to-STK35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STK35 versus PCAT6 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK35→partner) and Y-score (partner→STK35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCAT6 →	+0.771	+0.373	.002	.003	3	3
LSCC	MRPS26 →	+0.514	+0.204	<.001	<.001	3	3
CCRCC	DNAJA4 →	-1.246	-0.776	<.001	.001	3	2
LSCC	SLX4IP →	+0.317	+0.194	.002	<.001	3	2
UCEC	SOGA1 →	+0.753	+0.445	.003	.006	3	2
UCEC	TRANK1 →	-0.659	-0.352	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,034 associations by consensus.

STK35 vs PCAT6 — UCEC

Explore this scatter interactively →