STK33

Across TCGA cell cohorts, STK33 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,700 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible STK33-associated GO terms across cancer lineages are Manchette assembly, Germ cell development, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with STK33 in more than 12 cancer types. Because this analysis shows association rather than direction, both STK33-to-partner and partner-to-STK33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Manchette assembly grouped by STK33-low versus STK33-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STK33→partner) and Y-score (partner→STK33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Manchette assembly →	+1.057	+1.162	<.001	<.001	3	13
BONE	Germ cell development →	-0.035	-0.896	.002	.004	3	11
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.102	+1.566	.001	.003	2	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of telomere maintenance via telomerase →	+0.077	+1.174	.001	.002	3	10
OVARY	Action potential →	-0.076	-1.211	<.001	.001	3	10
SKIN	RNA splicing, via transesterification reactions →	+0.059	+0.917	.001	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,700 associations by consensus.

Manchette assembly by STK33 expression — BLOOD_Myeloma

Explore this box plot interactively →