Across TCGA patient cohorts, STK31 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK31-associated genes across cancer lineages are Caspase-7-cleavedD198, ACC1, and ERK2. Each is linked with STK31 in more than 2 cancer types. Because this analysis shows association rather than direction, both STK31-to-partner and partner-to-STK31 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK31→partner) and Y-score (partner→STK31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.939	+2.824	.006	.034	3	3
SKCM	ACC1 →	+0.254	+1.343	.002	.002	3	3
UCEC	ERK2 →	+0.143	+1.473	.015	.006	3	2
SKCM	p90 RSK →	+0.179	+1.415	.001	.007	3	2
UCEC	TFRC →	+0.437	+1.263	.007	.019	3	2
UCEC	XBP1 →	-0.132	-1.752	.002	.011	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

STK31 survival (RNA) · tumor vs normal (RNA) · all STK31 data types