Across TCGA cell cohorts, STK31 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STK31-associated genes across cancer lineages are GPR171, DEFA1, and PABPN1L. Each is linked with STK31 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK31-to-partner and partner-to-STK31 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK31→partner) and Y-score (partner→STK31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GPR171 →	+0.070	+3.584	.004	.008	3	1
OESOPHAGUS	DEFA1 →	+0.071	+3.392	<.001	.007	3	1
SKIN	PABPN1L →	+0.020	+3.678	<.001	.001	3	1
LARGE_INTESTINE	VAPA →	+0.620	+3.502	<.001	.001	3	1
LARGE_INTESTINE	BET1 →	+0.434	+2.451	.007	.009	3	1
LARGE_INTESTINE	BLVRA →	+1.373	+2.451	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

Exploration

STK31 survival (RNA) · tumor vs normal (RNA) · all STK31 data types