STK24

Across TCGA pan-cancer cohorts, STK24 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated STK24 data layer compared with 19 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher STK24 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated STK24 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

LSCC, UCEC, and GBM are the cancer types where STK24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.660	0.870	.011	10	view →
UCEC	DFS	Tertile	All	0.980	0.835	.011	10	view →
GBM	DFS	Quartile	All	0.238	0.488	.002	8	view →
HNSC	OS	Median	III,IV	1.000	0.484	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

STK24–LSCC (OS)

Open the LSCC breakdown →