Across TCGA pan-cancer cohorts, STK24-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated STK24-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher STK24-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STK24-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

ACC, LIHC, and KIRC are the cancer types where STK24-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.188	0.688	<.001	87	view →
LIHC	DFS	Tertile	All	0.347	0.500	.001	55	view →
KIRC	DFS	Tertile	All	0.516	0.711	.004	46	view →
UCS	DFS	Quartile	II,III,IV	0.660	0.215	.003	42	view →
PAAD	DFS	Quartile	All	0.505	0.154	<.001	41	view →
ESCA	DFS	Median	II,III,IV	0.358	0.604	<.001	36	view →
BRCA	OS	Quartile	All	0.987	0.942	.002	26	view →
STAD	DFS	Tertile	IV	0.112	0.773	<.001	21	view →
THCA	DFS	Tertile	All	0.933	0.747	<.001	16	view →
MESO	DFS	Median	III,IV	0.233	0.607	.021	15	view →
KIRP	DFS	Tertile	All	0.949	0.545	.012	14	view →
PRAD	DFS	Quartile	All	0.763	0.902	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

Exploration

Same gene, other analysis: STK24-AS1 tumor-vs-normal RNA expression · all STK24-AS1 data types