STK19

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STK19 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK19-associated genes across cancer lineages are Hepatocytes, MEP, and Macrophages. Each is linked with STK19 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK19-to-partner and partner-to-STK19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK19→partner) and Y-score (partner→STK19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMHepatocytes →-0.013-1.694.028.04431
SKCMMEP →+0.026+2.341.021.01931
UCECMacrophages →+0.033+2.224<.001.03231
UCECSkeletal muscle →+0.055+2.818.040.03731
UCECaDC →+0.127+2.818.004.03711
UCECMacrophages M1 →+0.038+2.818<.001.03711
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

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