Across TCGA cell cohorts, STK19 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STK19-associated genes across cancer lineages are OR52B4, ECE2, and GPR101. Each is linked with STK19 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK19-to-partner and partner-to-STK19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK19→partner) and Y-score (partner→STK19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR52B4 →	+0.017	+4.643	<.001	.004	3	1
LARGE_INTESTINE	ECE2 →	+0.323	+4.054	<.001	.004	3	1
LUNG_NSCLC_LUAD	GPR101 →	+0.012	+4.887	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

STK19 survival (RNA) · tumor vs normal (RNA) · all STK19 data types