STK11IP

Across TCGA pan-cancer cohorts, STK11IP mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated STK11IP data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher STK11IP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated STK11IP expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

PDAC, LSCC, and HNSC are the cancer types where STK11IP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	II,III,IV	0.673	0.828	.010	15	view →
LSCC	DFS	Median	All	0.616	0.837	.018	11	view →
HNSC	OS	Quartile	II,III,IV	0.857	0.612	.023	5	view →
LUAD	DFS	Median	III,IV	0.426	0.976	.005	4	view →
GBM	OS	Tertile	All	0.304	0.511	.023	2	view →
CCRCC	OS	Tertile	All	1.000	0.935	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

STK11IP–PDAC (DFS)

Open the PDAC breakdown →