STIP1

Across TCGA pan-cancer cohorts, STIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated STIP1 data layer compared with 28 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher STIP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated STIP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

CCRCC, PDAC, and UCEC are the cancer types where STIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.741	0.938	.003	26	view →
PDAC	DFS	Median	II,III,IV	0.825	0.639	.003	13	view →
UCEC	OS	Median	III,IV	1.000	0.494	.016	8	view →
HNSC	OS	Tertile	All	1.000	0.952	.033	4	view →
LUAD	OS	Quartile	II,III,IV	1.000	0.822	.030	2	view →
LSCC	DFS	Quartile	III,IV	0.612	0.958	.016	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

STIP1–CCRCC (OS)

Open the CCRCC breakdown →