STIP1

Across TCGA cell cohorts, STIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,929 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible STIP1-associated GO terms across cancer lineages are Positive regulation of attachment of mitotic spindle microtubules to kinetochore, Mitotic spindle elongation, and Spindle elongation. Each is linked with STIP1 in more than 18 cancer types. Because this analysis shows association rather than direction, both STIP1-to-partner and partner-to-STIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of attachment of mitotic spindle microtubules to kinetochore grouped by STIP1-low versus STIP1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STIP1→partner) and Y-score (partner→STIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.218	+0.986	<.001	<.001	3	19
SOFT_TISSUE	Mitotic spindle elongation →	+0.291	+1.025	<.001	<.001	3	19
SOFT_TISSUE	Spindle elongation →	+0.290	+0.972	<.001	<.001	3	19
SOFT_TISSUE	Mitotic spindle midzone assembly →	+0.291	+1.025	<.001	<.001	3	19
SOFT_TISSUE	DNA replication initiation →	+0.174	+0.781	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.250	+1.190	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,929 associations by consensus.

Positive regulation of attachment of mitotic spindle microtubules to kinetochore by STIP1 expression — BREAST

Explore this box plot interactively →