Across TCGA pan-cancer cohorts, STING1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated STING1 data layer compared with 20 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher STING1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated STING1 expression acts as an unfavorable survival marker.

STAD and LIHC are the cancer types where STING1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	III,IV	0.003	0.633	<.001	12	view →
LIHC	OS	Median	All	0.177	0.783	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: STING1 tumor-vs-normal RNA expression · all STING1 data types