Across TCGA patient cohorts, STING1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,465 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STING1-associated genes across cancer lineages are JAML, RNASE6, and CYTH4. Each is linked with STING1 in more than 6 cancer types. Because this analysis shows association rather than direction, both STING1-to-partner and partner-to-STING1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STING1→partner) and Y-score (partner→STING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	JAML →	+0.894	+0.503	<.001	<.001	3	7
GBM	RNASE6 →	+1.104	+0.586	<.001	<.001	3	7
OV	CYTH4 →	+0.733	+0.403	.002	<.001	3	6
OV	NCF4 →	+0.745	+0.361	.003	.005	3	6
LSCC	ARHGAP9 →	+0.960	+0.745	<.001	<.001	3	6
LSCC	PTPN22 →	+0.941	+0.677	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,465 associations by consensus.

Exploration

STING1 survival (RNA) · tumor vs normal (RNA) · all STING1 data types