Across TCGA patient cohorts, STING1 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,938 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STING1-associated proteins across cancer lineages are CD4, ENTPD1, and FOLR2. Each is linked with STING1 in more than 7 cancer types. Because this analysis shows association rather than direction, both STING1-to-partner and partner-to-STING1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STING1→partner) and Y-score (partner→STING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD4 →	+0.628	+0.371	<.001	<.001	3	8
BRCA	ENTPD1 →	+0.495	+0.452	<.001	<.001	3	8
HNSC	FOLR2 →	+0.779	+0.396	<.001	<.001	3	8
GBM	HLA-DMA →	+0.767	+0.460	<.001	<.001	3	8
UCEC	ITGB2 →	+0.623	+0.489	<.001	<.001	3	8
HNSC	PTPRC →	+0.643	+0.399	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,938 associations by consensus.

Exploration

STING1 survival (RNA) · tumor vs normal (RNA) · all STING1 data types