Across TCGA patient cohorts, STING1 mutation is significantly associated with the RNA expression of many other genes, with 359 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STING1-associated genes across cancer lineages are RNU6-311P, ANAPC15P1, and REXO1L8P. Each is linked with STING1 in more than 2 cancer types. Because this analysis shows association rather than direction, both STING1-to-partner and partner-to-STING1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STING1→partner) and Y-score (partner→STING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-311P →	+0.601	+7.102	<.001	<.001	3	3
LIHC	ANAPC15P1 →	+0.135	+5.186	<.001	.007	3	2
COAD	REXO1L8P →	+0.036	+6.142	<.001	<.001	3	2
LUAD	DDX43P1 →	+0.063	+5.798	<.001	.003	3	2
PRAD	MIR3689C →	+0.413	+7.939	<.001	.008	3	2
LUSC	GTF3AP5 →	+0.067	+5.625	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 359 associations by consensus.

Exploration

STING1 survival (RNA) · tumor vs normal (RNA) · all STING1 data types