Across TCGA patient cohorts, STIMATE RNA expression is significantly associated with the protein abundance of many other proteins, with 9,142 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible STIMATE-associated proteins across cancer lineages are TWF2, DOCK10, and AIF1. Each is linked with STIMATE in more than 4 cancer types. Because this analysis shows association rather than direction, both STIMATE-to-partner and partner-to-STIMATE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STIMATE→partner) and Y-score (partner→STIMATE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TWF2 →	+0.237	+0.185	.004	.001	3	5
LUAD	DOCK10 →	+0.406	+0.223	<.001	<.001	3	4
LSCC	AIF1 →	+0.418	+0.158	.004	.009	3	4
CCRCC	FGD2 →	+0.405	+0.166	<.001	<.001	3	4
LSCC	ABI3 →	+0.388	+0.182	<.001	<.001	3	4
CCRCC	INPP4A →	+0.226	+0.201	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,142 associations by consensus.

Exploration

STIMATE survival (RNA) · tumor vs normal (RNA) · all STIMATE data types