Across TCGA patient cohorts, STIMATE mutation is significantly associated with the RNA expression of many other genes, with 1,459 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STIMATE-associated genes across cancer lineages are RNU1-17P, MLLT10P2, and DNM1P50. Each is linked with STIMATE in more than 1 cancer types. Because this analysis shows association rather than direction, both STIMATE-to-partner and partner-to-STIMATE results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STIMATE→partner) and Y-score (partner→STIMATE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-17P →	+0.205	+2.672	<.001	.002	3	2
UCEC	MLLT10P2 →	+0.107	+2.541	.005	.007	3	2
UCEC	DNM1P50 →	+0.037	+4.153	<.001	.005	3	2
UCEC	RPL23AP90 →	+0.272	+2.419	.008	.001	3	1
UCEC	CCL5 →	+1.487	+3.459	<.001	.005	3	1
UCEC	NUDT3 →	+0.395	+3.617	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,459 associations by consensus.

Exploration

STIMATE survival (RNA) · tumor vs normal (RNA) · all STIMATE data types