Across TCGA cell cohorts, STIMATE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,646 significant associations in total. CNS shows the largest number of these associations.

The most reproducible STIMATE-associated GO terms across cancer lineages are Endosomal transport, Cytosolic transport, and Activation of store-operated calcium channel activity. Each is linked with STIMATE in more than 14 cancer types. Because this analysis shows association rather than direction, both STIMATE-to-partner and partner-to-STIMATE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STIMATE→partner) and Y-score (partner→STIMATE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endosomal transport →	+0.057	+0.903	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.075	+0.714	<.001	.002	3	15
SKIN	Activation of store-operated calcium channel activity →	+0.115	+0.666	<.001	<.001	3	15
BREAST	Positive regulation of store-operated calcium channel activity →	+0.128	+0.943	<.001	<.001	3	14
LARGE_INTESTINE	Microtubule nucleation →	+0.146	+0.694	<.001	<.001	3	14
SOFT_TISSUE	Store-operated calcium entry →	+0.129	+0.630	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,646 associations by consensus.

Exploration

STIMATE survival (RNA) · tumor vs normal (RNA) · all STIMATE data types