STEAP3

Across TCGA cell cohorts, STEAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,655 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STEAP3-associated GO terms across cancer lineages are Actin filament organization, Protein secretion, and Negative regulation of Rho protein signal transduction. Each is linked with STEAP3 in more than 11 cancer types. Because this analysis shows association rather than direction, both STEAP3-to-partner and partner-to-STEAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament organization grouped by STEAP3-low versus STEAP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STEAP3→partner) and Y-score (partner→STEAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Actin filament organization →	+0.090	+1.625	.001	<.001	3	12
SOFT_TISSUE	Protein secretion →	+0.065	+1.644	<.001	<.001	3	12
BONE	Negative regulation of Rho protein signal transduction →	+0.152	+1.556	.008	.003	3	11
LIVER	Negative regulation of cytokine production involved in inflammatory response →	+0.158	+1.815	.002	.006	3	11
LUNG_NSCLC_LUSC	Regulation of cell-matrix adhesion →	+0.084	+1.486	<.001	<.001	3	11
BONE	Regulation of focal adhesion assembly →	+0.124	+1.490	.009	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,655 associations by consensus.

Actin filament organization by STEAP3 expression — BONE

Explore this box plot interactively →