STEAP2

mass-spec protein — tumor vs normal
Tumor vs Normalmass-specBox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, STEAP2 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of STEAP2’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where STEAP2 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types STEAP2 is over-expressed in tumor.

PDAC and LUAD are the cancer types where STEAP2 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STEAP2 mass-spec protein (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
PDACAllII,III,IV+0.436.0262view →
LUADAllAll+0.233.0012view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

STEAP2–PDAC

Tumor-vs-normal mass-spec protein box plot for STEAP2 in PDAC.

Open the PDAC breakdown →

Exploration