STEAP2

Across TCGA cell cohorts, STEAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,611 significant associations in total. BONE shows the largest number of these associations.

The most reproducible STEAP2-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Protein folding in endoplasmic reticulum, and Sterol catabolic process. Each is linked with STEAP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both STEAP2-to-partner and partner-to-STEAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by STEAP2-low versus STEAP2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STEAP2→partner) and Y-score (partner→STEAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cytoplasmic pattern recognition receptor signaling pathway →	+0.062	+1.105	<.001	<.001	3	7
BREAST	Protein folding in endoplasmic reticulum →	+0.083	+1.310	<.001	<.001	3	7
URINARY_TRACT	Sterol catabolic process →	-0.254	-1.448	<.001	<.001	3	7
BONE	Ovarian cumulus expansion →	+1.486	+2.509	<.001	<.001	3	7
URINARY_TRACT	Cholesterol catabolic process →	-0.254	-1.448	<.001	<.001	3	7
STOMACH	Cilium or flagellum-dependent cell motility →	-0.066	-2.279	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,611 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by STEAP2 expression — SOFT_TISSUE

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