STC1

Across TCGA patient cohorts, STC1 mutation is significantly associated with the RNA expression of many other genes, with 5,669 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STC1-associated genes across cancer lineages are RNU6-805P, ANKRD26P2, and EXOC7P1. Each is linked with STC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both STC1-to-partner and partner-to-STC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-805P grouped by STC1-low versus STC1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STC1→partner) and Y-score (partner→STC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-805P →	+0.385	+3.719	<.001	.008	3	3
READ	ANKRD26P2 →	+0.137	+5.421	<.001	.005	3	3
BLCA	EXOC7P1 →	+0.018	+4.314	<.001	.009	3	3
BLCA	RNA5SP215 →	+0.313	+4.859	<.001	.004	3	2
BLCA	SNORD116-29 →	+0.453	+3.758	<.001	.008	3	2
READ	RNU6-338P →	+0.526	+7.276	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,669 associations by consensus.

RNU6-805P by STC1 expression — BLCA

Explore this box plot interactively →