STAU2

Across TCGA patient cohorts, STAU2 mutation is significantly associated with the RNA expression of many other genes, with 1,089 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAU2-associated genes across cancer lineages are RNA5SP358, RN7SL483P, and RN7SL607P. Each is linked with STAU2 in more than 2 cancer types. Because this analysis shows association rather than direction, both STAU2-to-partner and partner-to-STAU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP358 grouped by STAU2-low versus STAU2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAU2→partner) and Y-score (partner→STAU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP358 →	+0.297	+5.569	<.001	<.001	3	3
BLCA	RN7SL483P →	+0.183	+5.497	<.001	.004	3	2
UCEC	RN7SL607P →	+0.210	+1.882	<.001	.001	3	2
UCEC	H3C10 →	+0.697	+2.928	.004	<.001	3	2
SKCM	SRP68 →	+0.497	+3.240	.009	.009	3	2
SKCM	NEK4P1 →	+0.045	+3.858	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,089 associations by consensus.

RNA5SP358 by STAU2 expression — LUAD

Explore this box plot interactively →