STAU2-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, STAU2-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of STAU2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where STAU2-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STAU2-AS1 is over-expressed in tumor, although a few such as HNSC and READ show the opposite, repressed pattern.

LIHC, LUAD, and UCEC are the cancer types where STAU2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STAU2-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LIHCMaleII,III,IV+0.304<.0019view →
LUADAllAll+0.388<.0017view →
UCECAllAll+0.528<.0016view →
LUSCAllAll+0.278<.0014view →
STADAllAll+0.181.0154view →
HNSCAllAll−0.156.0164view →
BRCAAllAll+0.124.0154view →
KIRCFemaleIV+0.283.0093view →
PAADMaleAll+0.360.0372view →
CHOLAllAll+0.295.0092view →
READAllAll−0.168.0311view →
COADAllIV−0.155.0401view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

STAU2-AS1–LIHC

Tumor-vs-normal expression box plot for STAU2-AS1 RNA in LIHC.

Open the LIHC breakdown →

Exploration