STAU1

Across TCGA pan-cancer cohorts, STAU1 mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of STAU1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where STAU1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types STAU1 is over-expressed in tumor.

COAD, HNSC, and LSCC are the cancer types where STAU1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STAU1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.630	<.001	11	view →
HNSC	Male	III,IV	+0.386	<.001	11	view →
LSCC	Male	All	+0.742	<.001	9	view →
LUAD	Female	II,III,IV	+0.694	<.001	9	view →
CCRCC	All	II,III,IV	+0.117	.001	6	view →
OV	All	All	+0.424	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

STAU1–COAD

Open the COAD breakdown →