STAU1

Across TCGA patient cohorts, STAU1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAU1-associated genes across cancer lineages are MEK1, Annexin-1, and ARID1A. Each is linked with STAU1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAU1-to-partner and partner-to-STAU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by STAU1-low versus STAU1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAU1→partner) and Y-score (partner→STAU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.517	+2.906	<.001	.001	3	2
UCEC	Annexin-1 →	+0.467	+1.584	.023	.036	3	2
UCEC	ARID1A →	-0.165	-1.992	.021	.009	3	2
UCEC	ATM →	-0.609	-1.584	<.001	.036	3	2
UCEC	Caspase-8 →	-0.231	-2.558	.019	.010	3	2
SKCM	HER2_pY1248 →	-0.143	-2.987	.048	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

MEK1 by STAU1 expression — UCEC

Explore this box plot interactively →