STAU1

Across TCGA cell cohorts, STAU1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. CNS shows the largest number of these associations.

The most reproducible STAU1-associated genes across cancer lineages are KIR2DL1, KRT27, and PRAMEF10. Each is linked with STAU1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAU1-to-partner and partner-to-STAU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIR2DL1 grouped by STAU1-low versus STAU1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAU1→partner) and Y-score (partner→STAU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	KIR2DL1 →	+0.120	+4.201	<.001	.003	3	1
CNS	KRT27 →	+0.410	+4.449	<.001	.001	3	1
CNS	PRAMEF10 →	+0.231	+4.169	<.001	.008	3	1
CNS	TRIM64B →	+0.352	+3.643	<.001	.007	3	1
CNS	FAM163B →	+0.078	+4.201	.001	.003	3	1
LUNG_NSCLC_LUAD	IFNA6 →	+0.015	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

KIR2DL1 by STAU1 expression — CNS

Explore this box plot interactively →