STAT2

Across TCGA cell cohorts, STAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,735 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STAT2-associated GO terms across cancer lineages are Macroautophagy, Regulation of macroautophagy, and Process utilizing autophagic mechanism. Each is linked with STAT2 in more than 19 cancer types. Because this analysis shows association rather than direction, both STAT2-to-partner and partner-to-STAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by STAT2-low versus STAT2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STAT2→partner) and Y-score (partner→STAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Macroautophagy →	+0.085	+1.344	<.001	<.001	3	20
STOMACH	Regulation of macroautophagy →	+0.073	+1.258	.001	<.001	3	20
STOMACH	Process utilizing autophagic mechanism →	+0.080	+1.168	<.001	<.001	3	20
STOMACH	Autophagy →	+0.080	+1.168	<.001	<.001	3	20
LARGE_INTESTINE	Vacuolar transport →	+0.063	+1.203	<.001	<.001	3	20
OESOPHAGUS	Golgi vesicle transport →	+0.066	+0.991	.002	.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,735 associations by consensus.

Macroautophagy by STAT2 expression — STOMACH

Explore this box plot interactively →