STARD9

Across TCGA cell cohorts, STARD9 mutation is significantly associated with the RNA expression of many other genes, with 502 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STARD9-associated genes across cancer lineages are TUBGCP2, PSMB11, and GCAT. Each is linked with STARD9 in more than 2 cancer types. Because this analysis shows association rather than direction, both STARD9-to-partner and partner-to-STARD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBGCP2 grouped by STARD9-low versus STARD9-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD9→partner) and Y-score (partner→STARD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TUBGCP2 →	+0.453	+2.376	.005	.009	3	3
BLOOD_Lymphoma	PSMB11 →	+0.010	+2.070	.008	.008	3	2
LARGE_INTESTINE	GCAT →	+1.454	+3.743	<.001	<.001	3	2
LARGE_INTESTINE	PHF7 →	+0.668	+2.714	.002	.002	3	2
LARGE_INTESTINE	SLC25A11 →	+0.575	+2.628	.001	.002	3	2
LARGE_INTESTINE	WRAP73 →	+0.504	+3.321	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 502 associations by consensus.

TUBGCP2 by STARD9 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →