STARD7

Across TCGA pan-cancer cohorts, STARD7 mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of STARD7’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where STARD7 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types STARD7 is over-expressed in tumor, although a few such as LUAD and CCRCC show the opposite, repressed pattern.

LUAD, CCRCC, and COAD are the cancer types where STARD7 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STARD7 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−0.455	<.001	9	view →
CCRCC	Male	All	−0.140	<.001	6	view →
COAD	All	All	+0.216	.007	5	view →
PDAC	All	IV	−0.603	.018	2	view →
OV	All	All	+0.333	.044	2	view →
HNSC	Male	IV	+0.223	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

STARD7–LUAD

Open the LUAD breakdown →