STARD5

Across TCGA patient cohorts, STARD5 protein abundance is significantly associated with the RNA expression of many other genes, with 15,188 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STARD5-associated genes across cancer lineages are IGHV3OR16-9, IGLV2-14, and IGLV2-11. Each is linked with STARD5 in more than 6 cancer types. Because this analysis shows association rather than direction, both STARD5-to-partner and partner-to-STARD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STARD5 versus IGHV3OR16-9 in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD5→partner) and Y-score (partner→STARD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IGHV3OR16-9 →	+1.159	+0.616	<.001	<.001	3	7
OV	IGLV2-14 →	+3.007	+0.442	.001	.005	3	5
OV	IGLV2-11 →	+3.476	+0.540	<.001	.003	3	5
OV	IGHV1-18 →	+4.135	+0.579	<.001	<.001	3	5
CCRCC	LINC02576 →	+0.538	+0.279	.004	.005	3	5
OV	IGKV1-16 →	+2.763	+0.469	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,188 associations by consensus.

STARD5 vs IGHV3OR16-9 — LSCC

Explore this scatter interactively →