STARD5

Across TCGA cell cohorts, STARD5 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STARD5-associated genes across cancer lineages are ITGAD and OR2D3. Each is linked with STARD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both STARD5-to-partner and partner-to-STARD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGAD grouped by STARD5-low versus STARD5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD5→partner) and Y-score (partner→STARD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OR2D3 →	+0.030	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ITGAD by STARD5 expression — LARGE_INTESTINE

Explore this box plot interactively →