STARD4-AS1

Across TCGA pan-cancer cohorts, STARD4-AS1 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated STARD4-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher STARD4-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated STARD4-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LAML show a favorable association.

HNSC, CESC, and UVM are the cancer types where STARD4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.429	0.291	<.001	101	view →
CESC	DFS	Tertile	All	0.751	0.873	<.001	64	view →
UVM	DFS	Tertile	All	0.357	0.820	.002	54	view →
MESO	DFS	Tertile	All	0.303	0.509	.002	42	view →
STAD	OS	Median	All	0.369	0.685	.002	42	view →
BLCA	DFS	Quartile	All	0.448	0.694	.009	31	view →
THCA	OS	Median	All	0.961	1.000	.006	31	view →
KICH	OS	Tertile	All	0.726	1.000	.006	30	view →
LAML	DFS	Quartile	All	0.736	0.371	<.001	30	view →
ACC	OS	Median	II,III,IV	0.399	0.734	.002	25	view →
READ	OS	Tertile	II,III,IV	0.867	0.337	.005	22	view →
THYM	OS	Tertile	All	1.000	0.711	.003	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

STARD4-AS1–HNSC (OS)

Open the HNSC breakdown →