STARD3NL

Across TCGA pan-cancer cohorts, STARD3NL mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated STARD3NL data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher STARD3NL mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated STARD3NL expression acts as an unfavorable survival marker.

HNSC, UCEC, and LSCC are the cancer types where STARD3NL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.313	0.806	.007	10	view →
UCEC	DFS	Tertile	II,III,IV	0.567	1.000	.022	8	view →
LSCC	DFS	Tertile	All	0.642	0.927	.006	7	view →
COAD	DFS	Quartile	III,IV	0.537	1.000	.038	6	view →
CCRCC	DFS	Quartile	II,III,IV	0.278	0.746	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

STARD3NL–HNSC (DFS)

Open the HNSC breakdown →