STARD3NL

Across TCGA patient cohorts, STARD3NL mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STARD3NL-associated genes across cancer lineages are INPP4B, JNK_pT183_Y185, and Ku80. Each is linked with STARD3NL in more than 1 cancer types. Because this analysis shows association rather than direction, both STARD3NL-to-partner and partner-to-STARD3NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by STARD3NL-low versus STARD3NL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD3NL→partner) and Y-score (partner→STARD3NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.328	-3.169	.043	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.204	-2.308	.015	.036	3	1
UCEC	Ku80 →	+0.402	+3.472	<.001	.002	3	1
UCEC	Notch1 →	+0.211	+2.321	.002	.035	3	1
UCEC	PDCD4 →	-0.567	-2.321	.016	.035	3	1
UCEC	Rab25 →	-0.390	-2.321	.019	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

INPP4B by STARD3NL expression — UCEC

Explore this box plot interactively →